OpenFlexure Microscope

(openflexure.org)

67 points | by o4c 6 days ago

7 comments

  • gnabgib 6 days ago
    Popular in:

    2024 (189 points, 20 comments) https://news.ycombinator.com/item?id=42115243

    2021 (113 points, 39 comments) https://news.ycombinator.com/item?id=27216452

    • ChuckMcM 18 hours ago
      Yeah, the user 'o4c' appears to be a bot that reposts things that have been previously popular.
      • o4c 8 hours ago
        Hello, first of all sorry. I am not bot, a human user.

        I was searching for open source DIY microscope projects and found the OpenFlexure Microscope as the first search result. After reading through the project and finding it technically interesting, I submitted it to Hacker News. Fortunately, it reached the front page approximately five days after submission.

        If you search for the term “open source microscope,” you will see the same link appearing as the top result.

        https://www.google.com/search?q=open+source+microscope&oq=op...

        From my observation, information related to precision engineering is not widely known and can be difficult to find. Because of this, overlapping submissions can sometimes occur. I apologize if this caused any repetition. Detailed teardowns of precision instruments such as gauges, metrology tools, and scientific equipment are relatively rare, which contributes to this situation.

  • nickparker 18 hours ago
    Fun old project but the technology has improved[0] since then.

    https://www.youtube.com/watch?v=MgQbPdiuUTw

    • Aurornis 15 hours ago
      Since you seem familiar with this space, are there any other open source well documented projects that I could look at? The nice part about OpenFlexure is the documentation and community. Would be great if I could find another project going the same direction, even if it’s up and coming.
  • augusteo 13 hours ago
    I don't work in hardware, but projects like this are inspiring. Taking something expensive and specialized and making it accessible with open designs.

    The WHO recognition for low-resource settings is the kind of impact that matters.

  • abdullahkhalids 15 hours ago
    The core of a microscope are the lenses. For this, you are required to buy three different ones [1]. One of these can be acquired from Thorlabs for 65 USD [2].

    How difficult would it be to build lenses of this quality "at home"?

    [1] https://build.openflexure.org/openflexure-microscope/v7.0.0-...

    [2] https://www.thorlabs.com/item/AC127-050-A

    • dekhn 14 hours ago
      It's not super practical to make objectives. While I suppose it's technically possible, what you produce will almost certainly be worse, more expensive, and more time-consuming.

      $65 for a good lens is really not a huge amount of money; you can also find slightly cheaper lenses (about $20 on aliexpress).

      To make a lens like this, you would have to buy a glass blank of the right type (two, actually- a doublet is made of two different types of glass), grind and polish them (very messy), and then bond them and apply an antireflective coating. Getting the lens geometry just right is very challenging. Or you can just give Thorlabs $65 and focus (ha) on building a microscope around it (I do this as a hobby; I'm sitting next to one of those lenses right now).

      However, folks do this, see http://www.microscopy-uk.org.uk/mag/indexmag.html?http://www... but I can tell you from the images that you could get the same results (better really) with a $150 microscope (which also embeds many hundreds of years of practical technology that make your experience significantly better).

      Also, if you're really keen on doing it yourself for pedagogical reasons, then have at it, I just don't think it's the best use of time.

  • jacquesm 12 hours ago
  • dekhn 14 hours ago
    If you have a 3d printer, I think one of the most practical things you can do is make UC2 cubes (or just buy them). It's simpler to print, a bit more flexible, and a good introduction to the various technologies.
  • anfractuosity 19 hours ago
    Another 3D printed microscope https://github.com/TadPath/PUMA looks very interesting too.